Comparison between Clinical and Bacteriological Profile of Febrile Neutropenic and Non Neutropenic Pediatric Leukemic Patients

Background: Infection is an important cause of morbidity and mortality in children with leukemia. To improve the quality care survival, it to understand clinical presentation bacteriological profile during febrile episodes these patients. The aim this study was compare neutropenic nonneutropenic pediatric leukemic Materials methods: This a cross sectional observational conducted at Chittagong Medical College Hospital (CMCH) over period 12 months. Study population (n=60) were all hospitalized patients who on anticancer chemotherapy. By purposive sampling two groups made. Group A (n=30) group B non-neutropenic Clinical presentation, antibiotics susceptibility patterns both analyzed. Results: Mean (±SD) age 6.41±3.05 years. Acute Myeloid Leukemia (AML) high Group-A (60%) Lymphoblastic (ALL) Group-B(80%). Gastroenteritis, skin infection sepsis more than (p<0.05). Upper respiratory tract infections significantly Among 60 samples, 7 (12%) blood culture positive for bacteria. isolated organisms E. coli, Klebsiellaspp, Salmonella, Staph aureus others. Amikacin Meropenem Vancomycin effective agents. Conclusion: Febrile common AML undergoing Gram negative sepsis, gastroenteritis neutropenia, but upper non neutropenia. JCMCTA 2021 ; 32 (2) : 25-29